The LIPES project

A short film to explain the LIPES project rationale and outcomes.

LIPES project day event @ BIOKET 2021

A series of videos on key topics of the LIPES project has been elaborated and presented at the occasion of the LIPES project day event @ BIOKET in March 2021.



LIPES process chemistry



LIPES Enzyme development



LIPES Demo plant design






LIPES End products Overview

About the project


  • To perform the scale-up to pre-industrial level of a new environmentally friendly alternative to the traditional and current splitting routes of triglyceride producing free fatty acids and glycerol, thus at a lower variable and investment costs and in very resource-efficient way with a minimum saving of 45% water consumption, 70% of enzymes and 80% of energetic consumption
  • To enzymatically produce selected commercially important fatty acids at an overall lower variable cost than the current processes and to showcase their use as intermediates in a wider range of application.
  • To contribute to reaching the EC goals on waste reduction by elaborating and evaluating new value chains for making use of agricultural co-products

Expected impacts

  • Strengthen the competitiveness of EU oleo-chemicals industry in a context of growing competition with Asian bio-based products through a cost effective process leading to high performance products
  • Sustainable and innovative integrated new process leading to high quality products along the whole value chain
  • Competitive biotech pathway & process as compared to the conventional processes
  • Selection of enzyme(s) selective for vegetable oil hydrolysis
  • Efficient enzyme for enzymatic splitting of oils
  • New low trans FA for food application High quality FA
  • New grade of dimer acids (C36 and C44)
  • New grade of Co-polyesters co-products

Interaction between different Work Packages

Interactions between partners




Project coordinator: Yann RAOUL (yann.raoul@oleon.com)



STC-Engineering Gmbh is a private owned company for process plant design and construction established in 1999. STC is one of the few known engineering companies with the core competence in mixing technology including own R&D competence in mixing. This fact favours the whole process design and its technical imlementation. STC was involved and in leading position for the mixing and system topics for new products e.g. biodiesel, sundiesel, biogas, bioethanol as well as new processes per se for e.g. catalyst deactivation. STC represents the entire spectrum of plant in existing structures. STC had been involved already in different production steps for oleo-chemistry in Malaysia.



Starting from natural, renewable raw materials, Oleon manufactures a broad range of natural chemicals with various characteristics to respond to many application needs and the most demanding requirements. We offer our customers renewable, environmentally-friendly and biodegradable ingredients for their processes. Oleon is the European leader in oleochemistry. Our state-of-the art plants produce fatty acids, glycerine, bio-MPG, dimers, fatty esters and further specialties based on natural oils and fats. Our global presence and dedicated employees enable Oleon to offer sustainable solutions with excellent customer support.



Biocatalysts is a global biotechnology company producing speciality enzymes at commercial scales for a variety of industries, such as food, flavor & fragrances, pharmaceutical, life science, fine chemicals and many more. 

We offer both off-the-shelf enzyme products and a customised enzyme discovery, development and manufacturing service. The latter is where we excel, identifying en enzyme exists as a concept on a database or mined from our metagenomics library, through to producting large scale commercial quantities of stable enzymes suitable for global shipment. 

Biocatalysts has a wealth of enzyme knowledge and experience due to being in the business for over 30 years. This, along with our continous investment in new technology and capabilities, enables us to exceed our customers's enzyme expectations. 


ABOUT DSM COMPANY _ DSM Bright Science, Brighter Living™

Royal DSM is a global science-based company active in health, nutrition and materials. By connecting  its unique compétences in Life Sciences and Materials Sciences, DSM is driving economic prosperity, environmental progress and social advances to create sustainable value for all stakeholders simultaneously. DSM delivers innovative solutions that nourish, protect and improve performance in global markets such as food and dietary suppléments, personal care, feed, medical devices, automotive, paints, electrical and electronics, life protection, alternative energy and bio-based materials.

DSM and its associated companies deliver annual net sales of about €10 billion with approximately 25,000 employees. The company is listed on Euronext Amsterdam. More information can be found at www.dsm.com

Project Timeline

Start date: End date:
September 1, 2016 December 31, 2021


BBI JU contribution: Total Budget:
4,295,153.67 € 6 057 500 €